Epistasis is a crucial issue: Non-Linear responses can hinder drug target identification or optimization of industrial production processes

15 December 2022

Protein engineering in the context of metabolic engineering has a growing impact in industrial biotechnology and synthetic biology. Epistasis is a crucial issue: Non-Linear responses can hinder drug target identification or optimization of industrial production processes.

Discover our Editorial for a special issue of Frontiers in Molecular Biosciences: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways VOL I.

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